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Mixture of Propylene Glycol Ester Of Cetrizine Diastereomer
● In Stock
| Catalogue No.: | VE009372 |
|---|---|
| CAS No.: | N/A |
| Mol. Formula: | C24H31ClN2O4 |
| Mol. Weight: | 447.00 g/mol |
Additional information on Mixture of Propylene Glycol Ester Of Cetrizine Diastereomer
Parent drug
CetirizineIUPAC Name
1-Hydroxypropan-2-yl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate compound with 2-hydroxypropyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetate (1:1)Synonyms
N/ASmiles
O=C(OCC(O)C)COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1InChI
InChI=1S/C24H31ClN2O4/c1-19(28)17-31-23(29)18-30-16-15-26-11-13-27(14-12-26)24(20-5-3-2-4-6-20)21-7-9-22(25)10-8-21/h2-10,19,24,28H,11-18H2,1H3Description
Mixture of Propylene Glycol Ester Of Cetrizine Diastereomer standard is a well-characterized compound that aligns with key regulatory guidelines, including USP, EMA, JP, and BP. It plays a crucial role in analytical method development, method validation (AMV), and quality control (QC) processes, particularly in the manufacturing of Cetirizine. This impurity standard is valuable for both Abbreviated New Drug Applications (ANDA) and New Drug Applications (NDA), ensuring reliable and precise analytical outcomes. A mixture of Propylene Glycol Ester Of Cetrizine Diastereomer or 1-Hydroxypropan-2-yl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazine-1-yl)ethoxy)acetate compound with 2-hydroxypropyl 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazine-1-yl)ethoxy)acetate (1:1), is a selective Histamine-1 antagonist, it is used in the treatment sneezing, coughing, nasal congestion, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, the volume of distribution: 0.44 and plasma protein binding is 93%.
References
Naqvi, Aasim, and Valerie Gerriets. “Cetirizine.†Nih.gov, StatPearls Publishing, 27 Nov. 2021, www.ncbi.nlm.nih.gov/books/NBK549776/. ‌Request a Quote
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