N-Nitroso Dobutamine
N Nitroso dobutamine or N-(3,4-Dihydroxyphenethyl)-N-(4-(4-hydroxyphenyl)butane-2-yl)nitrous amide is a metabolite of dobutamine which is a sympathomimetic amine which is an inotropic agent evaluated for use in congestive heart failure. Dobutamine elevates cardiac output by selectively augmenting stroke volume, and this is accompanied by a diminished total peripheral vascular resistance that is controlled by the reflex withdrawal of sympathetic tone to the vasculature.
Additional information on N-Nitroso dobutamine
VE007836
N/A
C18H22N2O4
330.38 g/mol
Dobutamine
N-(3, 4-Dihydroxyphenethyl)-N-(4-(4-hydroxyphenyl)butan-2-yl)nitrous amide
N/A
Wheatley, T., and G. R. Park. “Acute Respiratory Insufficiency from Psittacosis.” BMJ, vol. 291, no. 6487, July 1985, pp. 53–54, https://doi.org/10.1136/bmj.291.6487.53-b.?Ruffolo, R. R. “The Pharmacology of Dobutamine.” The American Journal of the Medical Sciences, vol. 294, no. 4, Oct. 1987, pp. 244–48, https://doi.org/10.1097/00000441-198710000-00005.?
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