N-Nitroso dobutamine

N Nitroso dobutamine or N-(3,4-Dihydroxyphenethyl)-N-(4-(4-hydroxyphenyl)butane-2-yl)nitrous amide is a metabolite of dobutamine which is a sympathomimetic amine which is an inotropic agent evaluated for use in congestive heart failure. Dobutamine elevates cardiac output by selectively augmenting stroke volume, and this is accompanied by a diminished total peripheral vascular resistance that is controlled by the reflex withdrawal of sympathetic tone to the vasculature.

Additional information

Catalogue No.

VE007836

CAS No.

N/A

Molecular Formula

C18H22N2O4

Molecular Weight

330.38 g/mol

IUPAC Name

N-(3, 4-Dihydroxyphenethyl)-N-(4-(4-hydroxyphenyl)butan-2-yl)nitrous amide

References

Wheatley, T., and G. R. Park. “Acute Respiratory Insufficiency from Psittacosis.” BMJ, vol. 291, no. 6487, July 1985, pp. 53–54, https://doi.org/10.1136/bmj.291.6487.53-b.?Ruffolo, R. R. “The Pharmacology of Dobutamine.” The American Journal of the Medical Sciences, vol. 294, no. 4, Oct. 1987, pp. 244–48, https://doi.org/10.1097/00000441-198710000-00005.?

Status

In-stock