N-Nitroso N-Desbenzyl Nicardipine Impurity

It is one of impurity present in Nicardipine, Nicardipine is a dihydropyridine calcium-channel blocker, and is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal’s variant angina. Nicardipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, which is used for the treatment of hypertension and chronic stable angina.

Additional information on N-Nitroso N-Desbenzyl Nicardipine Impurity

Catalogue No.

VE0010197

CAS No.

N/A

Molecular Formula

C19H22N4O7

Molecular Weight

418.4 g/mol

Parent drug

Nicardipine

IUPAC Name

3-Methyl 5-(2-(methyl(nitroso)amino)ethyl) 2, 6-dimethyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate

Synonyms

N/A

References

Danielsson, Å., Bjerle, P., Ek, B., Steen, L., & Suhr, O. (1987). Nicardipine in the treatment of essential hypertension controlled 6-month-study comparing nicardipine with propranolol at rest and during exercise. European Journal of Clinical Pharmacology, 33(1), 15–20. https://doi.org/10.1007/bf00610373

Status

In-stock

[rfq_list]

Login first to add product to RFQ List

Request a quote

N-Nitroso N-Desbenzyl Nicardipine Impurity

N-Nitroso N-Desbenzyl Nicardipine Impurity
Catalogue No.

VE0010197

CAS No.

N/A

Molecular Formula

C19H22N4O7

Molecular Weight

418.4 g/mol

Parent drug

Nicardipine

IUPAC Name

3-Methyl 5-(2-(methyl(nitroso)amino)ethyl) 2, 6-dimethyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate

Synonyms

N/A

References

Danielsson, Å., Bjerle, P., Ek, B., Steen, L., & Suhr, O. (1987). Nicardipine in the treatment of essential hypertension controlled 6-month-study comparing nicardipine with propranolol at rest and during exercise. European Journal of Clinical Pharmacology, 33(1), 15–20. https://doi.org/10.1007/bf00610373

Status

In-stock

ListName

N-Nitroso N-Desbenzyl Nicardipine Impurity

Exclusively Supplied by Veeprho

Exclusively Supplied by Veeprho

"*" indicates required fields

Hidden
Products quotation
Name
Url
 
Hidden