73785-40-7: N-Nitrosocimetidine

N-Nitrosocimetidine (CAS No: 73785-40-7) or 3-cyano-1-methyl-2-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-1-nitrosoguanidine is a compound of Cimetidine. Cimetidine is a non-thiourea analogue of metiamide. It is a specific competitive histamine H2-receptor antagonist and is a good gastric secretion inhibitor in animals and humans. Cimetidine is one of few histamine H2-receptor antagonists with wide clinical application.

Additional information

Catalogue No.

VE008296

CAS No.

73785-40-7

Molecular Formula

C10H15N7OS

Molecular Weight

281.34 g/mol

IUPAC Name

3-cyano-1-methyl-2-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]-1-nitrosoguanidine

References

Muscroft, TimothyJ., et al. “CIMETIDINE IS UNLIKELY to INCREASE FORMATION of INTRAGASTRIC N-NITROSO-COMPOUNDS in PATIENTS TAKING a NORMAL DIET.” The Lancet, vol. 317, no. 8217, Feb. 1981, pp. 408–10, https://doi.org/10.1016/s0140-6736(81)91791-8. Brimblecombe, R. W., et al. “Cimetidine—a Non-Thiourea H2-Receptor Antagonist.” Journal of International Medical Research, vol. 3, no. 2, Mar. 1975, pp. 86–92, https://doi.org/10.1177/030006057500300205. Somogyi, Andrew, and Roland Gugler. “Clinical P

Status

In-stock