54237-72-8: Cimetidine EP Impurity E

54237-72-8: Cimetidine EP Impurity E

Also known as Cimetidine Sulfoxide it is the major metabolite of the H2-receptor antagonist Cimetidine. Cimetidine Sulfoxide is found in the blood and urine of patients having kidney diseases. Cimetidine is an H2 receptor antagonist. It is frequently prescribed for gastric and duodenal ulcer disease. Cimetidine has depicted anticancer effects.

Additional information on CAS 54237-72-8

Catalogue No.

VE006612
CAS No.

54237-72-8
Molecular Formula

C10H16N6OS
Molecular Weight

268.34
Parent drug

Cimetidine
IUPAC Name

2-Cyano-1-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl]-ethyl]guanidine
Synonyms

Cimetidine Sulfoxide
References

Lee, George Jia-Long, et al. “Rapid and Sensitive Determination of Enzymatic Degradation Products of Isomeric Chondroitin Sulfates by High-Performance Liquid Chromatography.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 146, no. 3, Nov. 1978, pp. 439–48, https://doi.org/10.1016/s0378-4347(00)81202-5. Lukša, J., and Dj. Josić. “Determination of Cimetidine in Human Plasma by Free Capillary Zone Electrophoresis.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 667, no. 2, May 1995, pp. 321–27, https://doi.org/10.1016/0378-4347(95)00032-e. Kubecova, Martina, et al. “Cimetidine: An Anticancer Drug?” European Journal of Pharmaceutical Sciences, vol. 42, no. 5, Apr. 2011, pp. 439–44, https://doi.org/10.1016/j.ejps.2011.02.004.
Status

In-stock

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54237-72-8: Cimetidine EP Impurity E

54237-72-8: Cimetidine EP Impurity E
Catalogue No.

VE006612
CAS No.

54237-72-8
Molecular Formula

C10H16N6OS
Molecular Weight

268.34
Parent drug

Cimetidine
IUPAC Name

2-Cyano-1-methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfinyl]-ethyl]guanidine
Synonyms

Cimetidine Sulfoxide
References

Lee, George Jia-Long, et al. “Rapid and Sensitive Determination of Enzymatic Degradation Products of Isomeric Chondroitin Sulfates by High-Performance Liquid Chromatography.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 146, no. 3, Nov. 1978, pp. 439–48, https://doi.org/10.1016/s0378-4347(00)81202-5. Lukša, J., and Dj. Josić. “Determination of Cimetidine in Human Plasma by Free Capillary Zone Electrophoresis.” Journal of Chromatography B: Biomedical Sciences and Applications, vol. 667, no. 2, May 1995, pp. 321–27, https://doi.org/10.1016/0378-4347(95)00032-e. Kubecova, Martina, et al. “Cimetidine: An Anticancer Drug?” European Journal of Pharmaceutical Sciences, vol. 42, no. 5, Apr. 2011, pp. 439–44, https://doi.org/10.1016/j.ejps.2011.02.004.
Status

In-stock
ListName

Cimetidine EP Impurity E
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