66-86-4: Neomycin Sulfate EP Impurity C

Neomycin Sulfate EP Impurity C (CAS No: 66-86-4) is an impurity present in Neomycin that exerts its antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis, it is effective against most gram-negative organisms.

Additional information on CAS 66-86-4

Catalogue No.

VE006929

CAS No.

66-86-4

Molecular Formula

C23H46N6O13

Molecular Weight

614.65

Parent drug

Neomycin

IUPAC Name

(2R, 3S, 4R, 5R, 6R)-5-amino-2-(aminomethyl)-6-(((2R, 3S, 4R, 5S)-5-(((1R, 2R, 3S, 5R, 6S)-3, 5-diamino-2-(((2R, 3R, 4R, 5S, 6R)-3-amino-6-(aminomethyl)-4, 5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3, 4-diol

Synonyms

N/A

References

Clarot, I., et al. “Analysis of Neomycin Sulfate and Framycetin Sulfate by High-Performance Liquid Chromatography Using Evaporative Light Scattering Detection.” Journal of Chromatography A, vol. 1087, no. 1-2, Sept. 2005, pp. 236–44, https://doi.org/10.1016/j.chroma.2005.05.054.?Sasseville, Denis. “Neomycin.” Dermatitis, vol. 21, no. 1, Jan. 2010, pp. 3–7, https://doi.org/10.2310/6620.2009.09073.?

Status

In-stock