2458-12-0: Nilotinib EP Impurity C

Status: In-stock

$49.00 - 300 mg

Nilotinib EP Impurity C (CAS No.2458-12-0) Or 3-Amino-4-methylbenzoic acid, Nilotinib EP Impurity C is an impurity present in Nilotinib, Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein, Nilotinib fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib, over-riding resistance caused by mutations, which is used in the treatment of various leukemias, including chronic myeloid leukemia.

*COA and Characterication data is always included with the product.
**This product is impurity reference standard for quantitative use.

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Additional information on CAS 2458-12-0

Catalogue No. VE009190
CAS No. 2458-12-0
Molecular Formula C8H9NO2
Molecular Weight 151.16 g/mol
Parent drug Nilotinib
IUPAC Name 3-Amino-4-methylbenzoic acid
Synonyms Nilotinib Related Compound C
Smiles CC1=C(C=C(C=C1)C(=O)OC)N
References "Blay, J.-Y., & von Mehren, M. (2011). Nilotinib: A Novel, Selective Tyrosine Kinase Inhibitor. Seminars in Oncology, 38, S3–S9. https://doi.org/10.1053/j.seminoncol.2011.01.016 ‌"
Status In-stock

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2458-12-0: Nilotinib EP Impurity C

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