Tranexamic EP Impurity A (Free Base)
Also known as Tranexamic BP Impurity A or Tranexamic Related Compound A or Tranexamic Acid Dimer (Free Base) is one of impurity present in Tranexamic, tranexamic acid is a synthetic derivative of lysine that act as antifibrinolytic effects by blocking lysine binding sites on plasminogen molecules. which shows inhibition of plasminogen activation results in stabilization of the preformed fibrin, also it reduces bleeding and improves clinical outcomes in the face of many different hemostatic challenges without a clear increase in thrombotic risk. Tranexamic acts on postpartum hemorrhage, trauma-associated hemorrhage, and surgical bleeding.
Additional information on Tranexamic EP Impurity A (Free Base)
trans, trans-4, 4?-(Iminodimethylene)di(cyclohexanecarboxylic)acid
Tranexamic BP Impurity A / Tranexamic Related Compound A / Tranexamic Acid Dimer (Free Base)
Cai, J., Ribkoff, J., Olson, S., Raghunathan, V., Al‐Samkari, H., DeLoughery, T. G., & Shatzel, J. J. (2019). The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. European Journal of Haematology, 104(2), 79–87. https://doi.org/10.1111/ejh.13348
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