448184-46-1: Vardenafil Related Compound E

Vardenafil Related Compound E (CAS No: 448184-46-1) Or 2-[2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5,1-f] [1,2,4]triazin-4(3H)-one, is an impurity of Vardenafil, Vardenafil is a benzenesulfonamide derivative, which is more potent and selective for PDE5, developed to treat erectile dysfunction.

Additional information

Catalogue No.

VE006875

CAS No.

448184-46-1

Molecular Formula

C21H28N6O4S

Molecular Weight

460.55

IUPAC Name

2-[2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl]-5-methyl-7-propylimidazo[5, 1-f] [1, 2, 4]triazin-4(3H)-one

Synonyms

Vardenafil N-Desethyl Impurity

References

Saenz de Tejada, I., Angulo, J., Cuevas, P., Fernández, A., Moncada, I., Allona, A., Lledó, E., Körschen, H., Niewöhner, U., Haning, H., Pages, E., & Bischoff, E. (2001). The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. International Journal of Impotence Research, 13(5), 282–290. https://doi.org/10.1038/sj.ijir.3900726

Status

In-stock