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1180132-17-5Abemaciclib Impurity 1
● 재고 있음
| 카탈로그 번호: | VE0017758 |
|---|---|
| CAS 번호: | 1180132-17-5 |
| 분자식: | C12H20N4 |
| 분자량: | 220.3 g/mol |
온라인 주문
에 대한 추가 정보 CAS 1180132-17-5
모약물
AbemaciclibIUPAC명
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-aminePharmacopeial Synonyms
N/A동의어
2-Pyridinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-; 2-Amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine; 5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-ylamine;SMILES
NC1=NC=C(CN2CCN(CC)CC2)C=C1InChI
InChI=1S/C12H20N4/c1-2-15-5-7-16(8-6-15)10-11-3-4-12(13)14-9-11/h3-4,9H,2,5-8,10H2,1H3,(H2,13,14)Shipping Condition
Ambient Temperature설명
Abemaciclib Impurity 1 (CAS 1180132-17-5) is a 2-pyridinamine derivative bearing a 5-(4-ethyl-1-piperazinyl)methyl substituent, also referenced as 2-amino-5-[(4-ethyl-1-piperazinyl)methyl]pyridine and 5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-ylamine. Its heterocyclic, multi-amine structure increases polarity and basicity relative to the parent API, which alters chromatographic retention, solubility and mass spectrometric ionization behavior. This process- and degradation-related impurity is critical for impurity profiling, method development and specification setting because of its potential impact on purity and stability. Characterization typically relies on orthogonal analytical approaches such as HPLC-UV and LC-MS to ensure accurate quantification and regulatory compliance.견적 요청
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와 관련된 기타 제품 Abemaciclib impurities
불순물 구조
모약물명
CAS 번호
불순물명
카탈로그 번호
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Abemaciclib
CAS No. N/A
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![6-[[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]amino]pyridine-3-carbaldehyde](https://veeprho.com/wp-content/uploads/2026/10/6-5-fluoro-4-7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-ylpyrimidin-2-ylaminopyridine-3-carbaldehyde-1627082-92-1-VZA000032.png "6-[[5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-yl]amino]pyridine-3-carbaldehyde")
Abemaciclib
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Cat No. VZA000032
![N-[5-[(4-ethyl-1-oxidopiperazin-1-ium-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine](https://veeprho.com/wp-content/uploads/2026/10/N-5-4-ethyl-1-oxidopiperazin-1-ium-1-ylmethyl-2-pyridinyl-5-fluoro-4-7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-ylpyrimidin-2-amine-NA-VZA000044.png "N-[5-[(4-ethyl-1-oxidopiperazin-1-ium-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine")
Abemaciclib
CAS No. N/A
Cat No. VZA000044
![1-Ethyl-4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)methyl)pyridin-3-yl)methyl)piperazine 1,4-dioxide](https://veeprho.com/wp-content/uploads/2024/11/VE0022183-1-Ethyl-4-6-5-fluoro-4-4-fluoro.png "1-Ethyl-4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)methyl)pyridin-3-yl)methyl)piperazine 1,4-dioxide")
Abemaciclib
CAS No. N/A
Cat No. VE0022183
