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포함 사항: HPLC, MASS/LC-MS, 1H NMR, FT-IR, 함량, 구조 규명 보고서(SER), 그리고 제품에 따라 추가 분석 데이터가 제공됩니다.

2484719-15-3Abiraterone Isopropyl Ether

● Under Development

카탈로그 번호:	VL830021
CAS 번호:	2484719-15-3
분자식:	C27H37NO
분자량:	391.6 g/mol

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모약물

Abiraterone

IUPAC명

3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine

약전 동의어

N/A

Other Synonyms

3-[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-3-propan-2-yloxy-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl]pyridine; 3.BETA.-ISOPROPOXY-17-(PYRIDIN-3-YL)ANDROSTA-5,16-DIENE; PYRIDINE, 3-(3-(1-METHYLETHOXY)ANDROSTA-5,16-DIEN-17-YL)-; Pyridine, 3-[3- (1- methylethoxy)androsta-5,16-dien-17-yl]-;

SMILES

C[C@@]12C(C3=CC=CN=C3)=CC[C@@]1([H])[C@]4([H])CC=C5C[C@@H](OC(C)C)CC[C@]5(C)[C@@]4([H])CC2

InChI

InChI=1S/C27H37NO/c1-18(2)29-21-11-13-26(3)20(16-21)7-8-22-24-10-9-23(19-6-5-15-28-17-19)27(24,4)14-12-25(22)26/h5-7,9,15,17-18,21-22,24-25H,8,10-14,16H2,1-4H3/t21-,22-,24-,25-,26-,27+/m0/s1

설명

Abiraterone Isopropyl Ether is a meticulously characterized reference material that complies with rigorous regulatory requirements, including those defined by USP, EMA, JP, and BP. This product plays a crucial role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Abiraterone. It is further supported by a detailed Structure Elucidation Report (SER), ensuring high accuracy and reliability across a broad range of analytical applications. Abiraterone Isopropyl Ether (CAS No: 2484719-15-3) might be present as an impurity of Abiraterone is a poorly water-soluble drug used in the treatment of prostate cancer that is discharged in the form of a prodrug of an acetate possessing slightly higher solubility than abiraterone in biorelevant media.

References

Gala, Urvi H., et al. â€œThe Effect of Drug Loading on the Properties of Abirateroneâ€“Hydroxypropyl Beta Cyclodextrin Solid Dispersions Processed by Solvent Free KinetiSolÂ® Technology.â€Â European Journal of Pharmaceutics and Biopharmaceutics, vol. 165, Aug. 2021, pp. 52â€“65, https://doi.org/10.1016/j.ejpb.2021.05.001.