Clorabacavir Racemic (CAS No: 1918156-05-4) is an impurity formed during the synthesis of Abacavir which is a nucleoside reverse transcriptase inhibitor used in the treatment of human immunodeficiency virus infection. It acts by inhibiting HIV reverse transcriptase by competing with the endogenous substrate dGTP.
References
Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.â€Â Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11.
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