Dolutegravir Impurities

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Impurity structure Parent Drug Name Name of Impurity Catalogue No. CAS No.
Dolutegravir (R,R)-Isomer Dolutegravir

Dolutegravir (R,R)-Isomer

VE009075 1357289-29-2
Dolutegravir (S,R)-Isomer Dolutegravir

Dolutegravir (S,R)-Isomer

VE0010364 1309560-49-3
Dolutegravir 2-Desfluoro Impurity Dolutegravir

Dolutegravir 2-Desfluoro Impurity

VE009433 1863916-88-4
Dolutegravir 4-Desfluoro 6-Fluoro Impurity Dolutegravir

Dolutegravir 4-Desfluoro 6-Fluoro Impurity

VE0011324 2244161-72-4
Dolutegravir 4-Desfluoro Impurity Dolutegravir

Dolutegravir 4-Desfluoro Impurity

VE0011325 1863916-87-3
Dolutegravir 4-Epimer Dolutegravir

Dolutegravir 4-Epimer

VE009074 1357289-37-2
Dolutegravir Desfluoro Impurity Dolutegravir

Dolutegravir Desfluoro Impurity

VE009802 2244161-71-3
Dolutegravir Dibenzyl Impurity Dolutegravir

Dolutegravir Dibenzyl Impurity

VE0011326 2244161-73-5
Dolutegravir Enantiomer Impurity (Na Salt) Dolutegravir

Dolutegravir Enantiomer Impurity (Na Salt)

VE0016542 1309575-43-6
Dolutegravir Impurity 12 Dolutegravir

Dolutegravir Impurity 12

VE0014455 N/A
Dolutegravir Impurity 13 Dolutegravir

Dolutegravir Impurity 13

VE0014456 N/A
Dolutegravir Impurity 14 Dolutegravir

Dolutegravir Impurity 14

VE0010357 2778347-47-8
Dolutegravir Impurity 18 Dolutegravir

Dolutegravir Impurity 18

VE0014457 N/A
Dolutegravir Impurity 2 Dolutegravir

Dolutegravir Impurity 2

VE0010358 N/A
Dolutegravir Impurity 23 Dolutegravir

Dolutegravir Impurity 23

VE0011329 1246616-73-8
Dolutegravir Impurity A Dolutegravir

Dolutegravir Impurity A

VE0010359 N/A
Dolutegravir Inhouse Impurity B Dolutegravir

Dolutegravir Inhouse Impurity B

VE008093 1973402-05-9
Dolutegravir Isopropyl Analouge Dolutegravir

Dolutegravir Isopropyl Analouge

VE008781 N/A
Dolutegravir O-Ethyl Impurity Dolutegravir

Dolutegravir O-Ethyl Impurity

VE008092 1802141-49-6
Dolutegravir O-Methyl Impurity Dolutegravir

Dolutegravir O-Methyl Impurity

VE0016540 1335210-35-9
Dolutegravir Propyl Analouge Dolutegravir

Dolutegravir Propyl Analouge

VE009122 N/A
Dolutegravir-D5 Dolutegravir

Dolutegravir-D5

DVE00533 N/A
Ethyl(4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate Dolutegravir

Ethyl(4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylate

VE0011330 N/A
(4R,12aR)-7 ethoxy 4 methyl  6,8 dioxo 3,4,6,8,12,12? hexahydro 2H pyrido[1',2':4,5]pyrazino[2,1 b][1,3]  oxazine 9 carboxylic acid Dolutegravir

(4R,12aR)-7 ethoxy 4 methyl 6,8 dioxo 3,4,6,8,12,12? hexahydro 2H pyrido[1',2':4,5]pyrazino[2,1 b][1,3] oxazine 9 carboxylic acid

VE0012732 N/A
(4R,12aS)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid Dolutegravir

(4R,12aS)-7-ethoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid

VE0011332 N/A
1,3-bis(2,4-difluorobenzyl)urea Dolutegravir

1,3-bis(2,4-difluorobenzyl)urea

VE0011328 N/A
2,4-Difluorobenzylamine Dolutegravir

2,4-Difluorobenzylamine

VE0011327 72235-52-0
5-ethoxy-6-(ethoxycarbonyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-3-carboxylic acid Dolutegravir

5-ethoxy-6-(ethoxycarbonyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyridine-3-carboxylic acid

VE0011331 N/A