Ramipril Impurities

Ramipril is used to treat high blood pressure either alone or in combination with other medications (hypertension).

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Parent Drug Name Name of Impurity Catalogue No.
Ramipril Ramipril EP Impurity A VL129001View CAS 108313-11-7
Ramipril Ramipril EP Impurity B VL129015View CAS 295328-72-2
Ramipril Ramipril EP Impurity C VL129005View CAS 99742-35-5
Ramipril Ramipril EP Impurity D VL129014View CAS 108731-95-9
Ramipril Ramipril EP Impurity E VL129009View CAS 87269-97-4
Ramipril Ramipril EP Impurity G VL129002View CAS 108-88-3
Ramipril Ramipril EP Impurity H VL129006View CAS 104195-90-6
Ramipril Ramipril EP Impurity I VL129007View CAS 129939-65-7
Ramipril Ramipril EP Impurity J VL129011View CAS 1246253-05-3
Ramipril Ramipril EP Impurity K VL129004View CAS 108736-10-3
Ramipril Ramipril EP Impurity L VL129008View CAS 1309040-96-7
Ramipril Ramipril EP Impurity M VL129012View CAS 2743-38-6
Ramipril Ramipril EP Impurity N VL129013View CAS 129939-63-5
Ramipril Ramipril EP Impurity O VL129003View CAS 151387-05-2
Ramipril Ramipril Impurity 2 VL129016View CAS 138877-09-5
Ramipril Ramipril impurity 1 VL129017View CAS 94498-85-8

Ramipril Related Compound

High blood pressure makes the heart and arteries work harder. If it persists for an extended period of time, the heart and arteries may cease to operate correctly.


  • “Ramipril: MedlinePlus Drug Information.” Medlineplus.gov, 2017, medlineplus.gov/druginfo/meds/a692027.html#:~:text=Ramipril%20is%20in%20a%20class,converting%20enzyme%20(ACE)%20inhibitors. Accessed 10 Mar. 2023. ‌
  • Janka. “Metabolic Effects of Ramipril Treatment in Hypertensive Subjects with Non-Insulin-Dependent Diabetes Mellitus.” Arzneimittel-Forschung, vol. 40, no. 4, Arzneimittelforschung, 2023, pubmed.ncbi.nlm.nih.gov/2141472/#:~:text=Also%2C%20a%20reduction%20in%20total,positive%20effect%20on%20lipid%20metabolism. Accessed 10 Mar. 2023. ‌
  • Doggrell, S. A. “Is Ramipril the Pril for Diabetes and Kidney Disease?” Drugs of Today, vol. 37, no. 5, 2001, p. 321, https://doi.org/10.1358/dot.2001.37.5.627954. Accessed 10 Mar. 2023. ‌


What is the therapeutic class of ramipril?

Ramipril is part of a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors.

Does ramipril use to treat high cholesterol?

Ramipril medication may result in a decrease in total cholesterol and an increase in HDL cholesterol. Its favorable effect on lipid metabolism might also be attributed to a reduction in body weight.

Does ramipril treat diabetes?

Ramipril has been shown to be useful in renal disease alone or in combination with diabetes, as well as in diabetes without kidney disease, and is the pril for diabetes and kidney disease.

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104195-90-6: Ramipril EP Impurity H

104195-90-6: Ramipril EP Impurity H
Catalogue No.




Molecular Formula


Molecular Weight


Parent drug



(2S, 3aS, 6aS)-1-(((R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl)octahydrocyclopenta[b]pyrrole-2-carboxylic acid


Ramipril (R, S-S, S, S)-Isomer / (1R)-Ramipril / Ramipril 1-Epimer


Herman, Linda L., et al. “Angiotensin Converting Enzyme Inhibitors (ACEI).” Nih.gov, StatPearls Publishing, 26 Dec. 2021, http://www.ncbi.nlm.nih.gov/books/NBK431051/.




Ramipril EP Impurity H

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