Impureza relacionada ao Citalopram: Citalopram Related Compound C (sal oxalato) | CAS 1440961-11-4 | é uma impureza de síntese e degradação que requer monitoração rigorosa em desenvolvimento e controle de qualidade. Estruturalmente caracterizada por um núcleo isobenzofuranona com substituição ciano e cadeia N-dimetilpropil ligada a um anel 4-fluorofenil formando o sal de oxalato | apresenta comportamento analítico desafiador em cromatografia líquida e espectrometria de massas devido a coeluições e padrões de fragmentação próximos ao ativo. Recomendam-se limites de aceitação definidos | métodos validados de quantificação e estudos de formação para mitigação de risco e conformidade regulatória.
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