1H | 1’H-[5 | 5′-biindole]-7 | 7′-diylbis((4-bromophenyl)methanone) | CAS 2192334-72-6 | é uma impureza observada em lotes de bromfenac | também referida como Bromfenac sodium Impurity 25 | BromfecImpurity62 | Bromfenac Impurity 62. Quimicamente caracterizada por estrutura biindólica com dois grupos benzofenona bromados | esta impureza apresenta massa molecular elevada e baixa solubilidade em meios aquosos | exigindo condições cromatográficas e espectrométricas otimizadas para identificação por HPLC | LC-MS e R-NMR. Sua presença pode impactar perfis de pureza e estabilidade do medicamento e requer investigação de origem | vias de formação e limites analíticos conforme requisitos de controle de qualidade e regulatórios.
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![1H,1'H-[5,5'-biindole]-7,7'-diylbis((4-bromophenyl)methanone)](https://veeprho.com/wp-content/uploads/2023/05/1H-1-H-5-5-biindole-7-7-diylbis-4-bromophenyl-methanone-sqr.png "1H,1'H-[5,5'-biindole]-7,7'-diylbis((4-bromophenyl)methanone)")
![(3,3'-dibromo-1H,1'H-[5,5'-biindole]-7,7'-diyl)bis((4-bromophenyl)methanone)](https://veeprho.com/wp-content/uploads/2023/05/3-3-dibromo-1H-1-H-5-5-biindole-7-7-diyl-bis-4-bromophenyl-methanone.png "(3,3'-dibromo-1H,1'H-[5,5'-biindole]-7,7'-diyl)bis((4-bromophenyl)methanone)")
