Cefazolin EP Impurity B (CAS 2384108-14-7) é uma impureza relacionada estruturalmente ao cefazolin | caracterizada por comportamento cromatográfico distintivo e por um padrão de fragmentação de massa que facilita sua identificação analítica. Detectável por HPLC com UV e por espectrometria de massa | apresenta propriedades físicas e químicas que indicam possível formação por degradação hidrolítica ou por reações de abertura de anel durante síntese e armazenamento. A presença desta impureza altera o perfil de pureza do API e exige especificações analíticas e limites de aceitação alinhados à farmacopéia para avaliação de conformidade e segurança.
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