4-Descyano 4-Bromo Citadiol (CAS 488148-10-3) é uma impureza identificada no processo sintético de produtos derivados de citadiol | gerada por desidratação incompleta e reações secundárias de bromação. O perfil físico-químico é caracterizado por espectrometria de massa e RMN | enquanto a quantificação rotineira utiliza HPLC com detector UV. Sua presença acima de limites aceitáveis pode comprometer a pureza | estabilidade e segurança do material | exigindo monitorização rigorosa em controle de qualidade. Estratégias de mitigação incluem otimização de etapas de purificação | validação de métodos analíticos e estabelecimento de especificações e limites de aceitação documentados em relatórios de lote.
Referências
“Escitalopram: MedlinePlus Drug Information.†Medlineplus.gov, 2022, medlineplus.gov/druginfo/meds/a603005.html#:~:text=Escitalopramisusedtotreat, monthsorlonger)inadults..
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