Impureza Anastrozol Monoamida Mononitrila (CAS 1338800-82-0) | também referida como Anastrozol Amida Nitrila | é um subproduto de síntese identificado durante a produção de anastrozol. Caracteriza-se por estrutura contendo grupos amida e nitrila que pode afetar o perfil de pureza e a estabilidade do lote. O acompanhamento quantitativo é realizado por técnicas analíticas robustas como HPLC com detector UV | LC-MS e RMN para confirmação estrutural | além de ensaios de impurezas relacionadas conforme ICH Q3A. Fornecemos material de referência e dados de especificação para suporte ao controle de qualidade | limites de aceitação e investigação de vias de formação para mitigação no processo.
Referências
Gangadhara, Sharath, and Gianfilippo Bertelli. “Long-Term Efficacy and Safety of Anastrozole for Adjuvant Treatment of Early Breast Cancer in Postmenopausal Women.†Therapeutics and Clinical Risk Management, vol. 5, 2009, pp. 291–300, www.ncbi.nlm.nih.gov/pmc/articles/PMC2690973/.
Solicitar orçamento
"*" indica campos obrigatórios
Outros produtos relacionados às Anastrozole impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
