Benserazide EP Impurity B (Free Base) | CAS 2472968-83-3 | identificado também como 2 | 2-Bis[(2 | 3 | 4-trihidroxifenil)metil]-DL-serina hidrazida | é uma impureza estruturalmente relacionada ao benserazide que impacta polaridade e solubilidade da matéria prima. Caracteriza-se pela presença de dois núcleos trihidroxifenílicos ligados a um resíduo de serina hidrazida em forma de base livre | exigindo monitoramento analítico detalhado. Sua identificação e quantificação dependem de HPLC com detecção UV e LC-MS para confirmação de massa | complementadas por NMR para elucidação estrutural. Avaliar estabilidade | perfis de degradação e limites aceitáveis é crítico para controle de qualidade e conformidade regulatória.
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