Informações adicionais sobre o Cefalexin EP Impurity F
Fármaco de origem
Cephalexin
Nome IUPAC
Sinônimos
Cephalexin Related Compound F (Trifluoroacetate)
Descrição
Cefalexin EP Impurity F | também denominada Cephalexin Related Compound F (Trifluoroacetate) | é uma impureza associada à produção de cefalexina gerada tipicamente por interação com ácido trifluoroacético durante etapas de síntese ou purificação. Caracteriza-se por um perfil analítico definido | detectável por HPLC e LC-MS | com sinais específicos em espectrometria de massa e ressonância magnética nuclear e comportamento cromatográfico alterado pelo contraíon trifluoroacetato. A presença influencia a pureza e o perfil de degradação do princípio ativo | exigindo quantificação por métodos validados | controle rigoroso de amostragem e condições de armazenamento para prevenir hidrólise e troca iônica.
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