Impureza Methyl 4-butyramido-5-methyl-2-nitrobenzoate | sinônimo 4-Butyrylamino-3-methyl-2-nitrobenzoic acid methyl ester | é uma impureza relacionada ao processo que apresenta massa molecular e sinais espectrais compatíveis com incorporação do grupo butiramido e substituição nitro no anel aromático. Detectada por LC-MS e HPLC com perfil de retenção distintivo | sua caracterização por RMN confirma padrões de acoplamento aromatico e sinais do éster metílico. Possui solubilidade em solventes orgânicos comuns e pode afetar a pureza e a estabilidade do produto final. Controle exige otimização da etapa sintética | purificação cromatográfica e monitoramento analítico com limites de aceitação bem definidos.
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