Impureza de Fenilefrina 3-hidroxibenzaldeído (CAS 100-83-4) é um aldeído aromático com fórmula C7H6O2 e massa molar 122 | 12 g/mol que pode formar-se durante etapas de oxidação parcial na síntese de fenilefrina. Como impureza crítica | compromete a pureza do API e exige monitorização por HPLC | GC-MS | LC-MS e RMN; apresenta reatividade pelo grupo aldeído e hidroxila | podendo afetar estabilidade e originar subprodutos. Fornecemos material de referência para validação analítica e estabelecimento de limites conforme guidelines ICH | com recomendações de armazenamento refrigerado | proteção contra luz e documentação para controle de qualidade.
Referências
Kong, Byung Soo, et al. “Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.†PLOS ONE, edited by Maria Cristina Vinci, vol. 11, no. 3, Mar. 2016, p. e0149394, https://doi.org/10.1371/journal.pone.0149394.
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