Impureza Sofosbuvir 2 (CAS 863329-62-8) é um subproduto identificado durante a síntese e purificação do Sofosbuvir | cuja monitoração é crítica para garantia de qualidade. Suas características físico-químicas e espectrais são definidas por HPLC | LC-MS e RMN | permitindo atribuição de massa | fragmentação e tempo de retenção. Estudos de estabilidade elucidam sua formação por vias degradativas ou por reações secundárias com solventes e reagentes | orientando limites de especificação e estratégias de remoção. Avaliação toxicológica | validação analítica robusta e controles de processo são recomendados para mitigar riscos e atender requisitos regulatórios.
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![Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]](https://veeprho.com/wp-content/uploads/2022/07/Sofosbuvir-5-Desphosphate-3-O-5BS-Phosphate5D.png "Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]")
