Impureza EP A da trazodona (sal de cloridrato) | CAS 55290-66-9 | também conhecida como Trazodona N-óxido (HCl) ou 4-(3-chlorophenyl)-1-(3-{3-oxo-2H | 3H-[1 | 2 | 4]triazolo[4 | 3-a]pyridin-2-yl}propyl)piperazin-1-ium-1-olate hydrochloride | é um subproduto identificado durante síntese e purificação da trazodona. Sua caracterização robusta por HPLC | LC-MS e RMN é essencial para estabelecer perfil de impurezas e critérios de aceitação conforme monografia EP. Estudos de estabilidade | solubilidade e comportamento do sal de cloridrato informam ações corretivas em processo e validação analítica. Fornece referência para investigação de desvios de processo e controle de qualidade de matérias primas e lotes industriais.
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