Valproic Acid EP Impurity A (CAS 109-52-4) | também conhecida como ácido valérico ou n-valeric acid | é uma impureza relevante no controle de qualidade do ácido valproico. Quimicamente um ácido carboxílico de cadeia linear | sua presença em níveis superiores aos limites monografados pode indicar degradação do princípio ativo ou falhas no processo de síntese. Caracteriza-se por polaridade e solubilidade em solventes orgânicos | detectável por HPLC com detecção UV | GC-MS e RMN para confirmação estrutural. O monitoramento quantitativo e a validação de métodos analíticos são essenciais para garantir conformidade com limites estabelecidos e minimizar riscos de estabilidade e segurança do produto final.
Referências
Reddy, S. Raghavender, et al. “Reliable GC Method for Related Substances in Divalproex Sodium Drug.” Journal of Chromatographic Science, vol. 55, no. 9, July 2017, pp. 891–98, https://doi.org/10.1093/chromsci/bmx057. ?
Solicitar orçamento
"*" indica campos obrigatórios
Outros produtos relacionados às Valproic Acid impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
