100 % Datengenauigkeit
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0 % Toleranz bei der Produktqualität
Lagerstandorte
- New Jersey, USA
- Czech Republic, EU
- Mumbai, India
* Vorbehaltlich Verfügbarkeit
Dokumentation
Enthält: HPLC, MASS/LC-MS, 1H-NMR, FT-IR, Gehalt, Structure Elucidation Report (SER) sowie zusätzliche analytische Daten je nach Produkt.
Abiraterone Sulfate Sodium Salt
● Under Development
| Katalog-Nr.:: | VL830037 |
|---|---|
| CAS-Nr.:: | N/A |
| Summenformel:: | C24H30NO4S. Na |
| Molare Masse:: | 451.57 g/mol |
Zusätzliche Informationen zu Abiraterone Sulfate Sodium Salt
Parent drug
AbirateroneIUPAC-Name
sodium (3S, 8R, 9S, 10R, 13S, 14S)-10, 13-dimethyl-17-(pyridin-3-yl)-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfatePharmakopöe-Synonyme
N/AOther Synonyms
(3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Sulfate SodiumSMILES
O=S(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)C(C5=CC=CN=C5)=CC[C@@]4([H])[C@]3([H])CC=C2C1)([O-])=O.[Na+]InChI
InChI=1S/C24H31NO4S.Na/c1-23-11-9-18(29-30(26,27)28)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23;/h3-5,7,13,15,18-19,21-22H,6,8-12,14H2,1-2H3,(H,26,27,28);/q;+1/p-1/t18-,19-,21-,22-,23-,24+;/m0./s1Beschreibung
Abiraterone Sulfate Sodium Salt (CAS No: 1993430-25-3) is an impurity of Abiraterone acetate that prevents the synthesis of testosterone by inhibition of 17a-hydroxylase. It is an antiandrogen drug approved for the treatment of metastatic castration-resistant prostate cancer.References
van Nuland, Merel, et al. “Development and Validation of an LC-MS/MS Method for the Simultaneous Quantification of Abiraterone, Enzalutamide, and Their Major Metabolites in Human Plasma.†Therapeutic Drug Monitoring, vol. 39, no. 3, June 2017, pp. 243–51, https://doi.org/10.1097/ftd.0000000000000387. ?Angebot anfordern
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Verunreinigungsstruktur
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