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포함 사항: HPLC, MASS/LC-MS, 1H NMR, FT-IR, 함량, 구조 규명 보고서(SER), 그리고 제품에 따라 추가 분석 데이터가 제공됩니다.

Abiraterone Sulfate Sodium Salt

● Under Development

카탈로그 번호:	VL830037
CAS 번호:	N/A
분자식:	C24H30NO4S. Na
분자량:	451.57 g/mol

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모약물

Abiraterone

IUPAC명

sodium (3S, 8R, 9S, 10R, 13S, 14S)-10, 13-dimethyl-17-(pyridin-3-yl)-2, 3, 4, 7, 8, 9, 10, 11, 12, 13, 14, 15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfate

약전 동의어

N/A

Other Synonyms

(3Î²)-17-(3-Pyridinyl)androsta-5,16-dien-3-ol Sulfate Sodium

SMILES

O=S(O[C@H]1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)C(C5=CC=CN=C5)=CC[C@@]4([H])[C@]3([H])CC=C2C1)([O-])=O.[Na+]

InChI

InChI=1S/C24H31NO4S.Na/c1-23-11-9-18(29-30(26,27)28)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23;/h3-5,7,13,15,18-19,21-22H,6,8-12,14H2,1-2H3,(H,26,27,28);/q;+1/p-1/t18-,19-,21-,22-,23-,24+;/m0./s1

설명

Abiraterone Sulfate Sodium Salt (CAS No: 1993430-25-3) is an impurity of Abiraterone acetate that prevents the synthesis of testosterone by inhibition of 17a-hydroxylase. It is an antiandrogen drug approved for the treatment of metastatic castration-resistant prostate cancer.

References

van Nuland, Merel, et al. â€œDevelopment and Validation of an LC-MS/MS Method for the Simultaneous Quantification of Abiraterone, Enzalutamide, and Their Major Metabolites in Human Plasma.â€ Therapeutic Drug Monitoring, vol. 39, no. 3, June 2017, pp. 243â€“51, https://doi.org/10.1097/ftd.0000000000000387. ?