Lagerstandorte

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Vorbehaltlich Verfügbarkeit

Dokumentation

MSDS herunterladen

Beispiel-COA herunterladen

Enthält: HPLC, MASS/LC-MS, 1H-NMR, FT-IR, Gehalt, Structure Elucidation Report (SER) sowie zusätzliche analytische Daten je nach Produkt.

62572-94-5Betaxolol EP Impurity B (Free Base)

● Auf Lager

Katalog-Nr.::	VL103014
CAS-Nr.::	62572-94-5
Summenformel::	C14H23NO3
Molare Masse::	253.34 g/mol

Angebot anfordern

Zur RFQ-Liste hinzufügen

Zusätzliche Informationen zu CAS 62572-94-5

Parent drug

Betaxolol/ Metoprolol

IUPAC-Name

(2RS)-1-[4-(2-Hydroxyethyl)phenoxy]-3-[(1-methylethyl)amino]propan-2-ol

Pharmacopeial Synonyms

Metoprolol EP Impurity H; O-Desmethyl Metoprolol; Betaxolol Hydroxyethyl Analog

Synonyme

1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneethanol

SMILES

CC(C)NCC(COC1=CC=C(C=C1)CCO)O

InChI

InChI=1S/C14H23NO3/c1-11(2)15-9-13(17)10-18-14-5-3-12(4-6-14)7-8-16/h3-6,11,13,15-17H,7-10H2,1-2H3

Shipping Condition

Ambient Temperature

Beschreibung

Metoprolol EP Impurity H (O-Desmethyl Metoprolol, Betaxolol Hydroxyethyl Analog), CAS 62572-94-5, is a structurally defined related impurity characterized by a 2-hydroxyethyl substitution on the phenoxy ring that increases polarity and modifies chromatographic properties compared with the parent substance. The free base 1-[4-(2-hydroxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol is readily identified and quantified using reversed-phase HPLC, LC-MS and proton NMR, exhibiting a distinct retention profile and diagnostic fragment ions. Monitoring this impurity supports impurity profiling, synthetic route assessment and stability evaluation where precise analytical standards and robust methods are required for regulatory control.