Thioctic Acid EP Impurity A (CAS 1204245-29-3) ist eine schwefelreiche verwandte Substanz der Liponsäure-Chemie und entspricht strukturell eher einem oxidativen oder prozessbedingten Transformationsprodukt als einer einfachen Fremdverunreinigung. Mit der Summenformel C8H14O2S3 und einer Molekülmasse von 238,4 g/mol enthält es ein disulfidbezogenes Trithiolangerüst, das Redoxverhalten und chromatographische Antwort beeinflussen kann. Die strukturelle Zuordnung und Quantifizierung erfordern typischerweise LC-MS/MS, hochauflösende LC-MS und, sofern die Flüchtigkeit dies zulässt, GC-MS. Im pharmakopöischen Verunreinigungsprofil wird diese Spezies als definierter Abbau- oder Synthesenebenprodukt bewertet.
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