Impureza G de citalopram (Citalopram EP Impurity G | CAS 1329745-98-3) | también referida como EsCitalopram EP Impurity G | es una impureza relacionada que aparece durante la síntesis y el proceso de purificación del citalopram. Su monitorización es crítica en el control de calidad farmacéutico y en el desarrollo de especificaciones compendiales. Esta impureza requiere identificación y cuantificación mediante técnicas analíticas robustas como HPLC con detección UV y LC-MS para establecer retención | perfil cromatográfico y espectros de masa. La caracterización permite evaluar riesgo tóxico | establecer límites de aceptación y optimizar procesos de escalado y purificación para cumplimiento regulatorio.
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