Escitalopram EP Impurity G (CAS 1329745-98-3) | conocido también como Citalopram ketone o 5-dimetilaminobutiril citalopram | es una impureza relevante en el perfil de calidad de escitalopram. Se origina típicamente por oxidación parcial o formación de subproducto durante etapas de síntesis y purificación | y presenta propiedades físicoquímicas y espectrales distintivas que permiten su identificación por HPLC con detección UV | LC-MS y RMN. El control cuantitativo y los métodos indicativos de estabilidad son esenciales para cumplir especificaciones compendiales | establecer límites aceptables y optimizar procesos de limpieza y purificación | minimizando su presencia en el material farmacéutico final.
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