Levodopa EP Impurity C (CAS 7636-26-2) | también conocida como Levodopa Related Compound B | 3-Methoxy-DL-tyrosine | 3-Methoxytyrosine | L-3-Methoxytyrosine o 3-(4-Hydroxy-3-methoxyphenyl)alanine | es una impureza relacionada estructuralmente con levodopa que aparece como subproducto de síntesis o por degradación al presentar un grupo metoxi en el anillo fenólico; su presencia puede afectar la pureza y el perfil de seguridad del principio activo. El control analítico de esta impureza es esencial y se realiza por HPLC con detección UV | complementado con LC-MS y NMR para confirmación estructural. Las estrategias de calidad incluyen límites específicos según guías ICH | procedimientos de purificación y medidas de prevención en proceso para mantener niveles aceptables en lotes liberados.
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