Sofosbuvir Impurity 23 (CAS 2041584-99-8) | 1-[(2R)-2-Deoxy-2-fluoro-2-methyl-a-D-erythro-pentofuranosyl]-2 | 4(1H | 3H)-pyrimidinedione | es una impureza relacionada estructuralmente con el núcleo nucleósido que requiere identificación y cuantificación precisas para el control de calidad. Su perfil analítico incluye huellas cromatográficas claras en HPLC y LC-MS | señales de resonancia específicas en NMR y patrones de fragmentación útiles para la elucidación estructural. La caracterización permite establecer límites de aceptación | procedimientos de muestreo y métodos de liberación | además de evaluar la estabilidad y formación durante síntesis y almacenamiento | asegurando cumplimiento con guías regulatorias y optimización de procesos.
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