612069-27-9Azithromycin EP Impurity E

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Catalogue No.:	VL186007
CAS No.:	612069-27-9
Mol. Formula:	C36H68N2O12
Mol. Weight:	720.93 g/mol

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Additional information on CAS 612069-27-9

Parent drug

Azithromycin

IUPAC Name

3-(N,N-didemethyl) Azithromycin

Synonyms

Amino Azithromycin; (2R, 3S, 4R, 5R, 8R, 10R, 11R, 12S, 13S, 14R)-11-[(3-Amino-3, 4, 6-trideoxy-?-D-xylo-hexopyranosyl)oxy]-13-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3, 4, 10-trihydroxy-3, 5, 6, 8, 10, 12, 14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one; Aminoazithromycin A; Aminoazithromycin Impurity E (EP) ;Azithromycin Impurity E; USP RRT 0.43

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Description

Also known as Azithromycin Impurity E, it is an impurity of Azithromycin. Azithromycin is the first member of a group that belongs to macrolide antibiotics called azalides. It is an effective therapeutic agent for the oral treatment of sexually transmitted diseases, upper and lower respiratory tract infections and skin structure infections.

References

Kwiecie?, Anna, et al. Stress Degradation Studies on Azithromycin and Development of a Validated Stability-Indicating TLC-Densitometric Method with HPLC/Electrospray Ionization-MS Analysis of Degradation Products.” Journal of AOAC INTERNATIONAL, vol. 95, no. 5, Sept. 2012, pp. 1418–24, https://doi.org/10.5740/jaoacint.10-196.