1075-89-4Buspirone EP Impurity K

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Catalogue No.:	VL249002
CAS No.:	1075-89-4
Mol. Formula:	C9H13NO2
Mol. Weight:	167.21 g/mol

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Additional information on CAS 1075-89-4

Parent drug

Buspirone

IUPAC Name

8-azaspiro[4.5]decane-7,9-dione

Pharmacopeial Synonyms

Buspirone Related Compound K

Other Synonyms

3,3-Tetramethyleneglutarimide; 1,1-Cyclopentanediacetimide; 4,4-Tetramethyleneglutarimide; 8-azaspiro(4.5)decane-7,9-dione; 3-Spirocyclopentaneglutarimide; 3-Spirocyclopentaneglutarimide; azaspirodecanedione

Smiles

O=C(NC(C1)=O)CC21CCCC2

InChI

InChI=1S/C9H13NO2/c11-7-5-9(3-1-2-4-9)6-8(12)10-7/h1-6H2,(H,10,11,12)

Shipping Condition

Ambient Temperature

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Description

Buspirone Related Compound K, CAS 1075-89-4, is a structurally defined small-molecule impurity associated with the arylpiperazine anxiolytic buspirone. With molecular formula C9H13NO2 and molecular weight 167.21 g/mol, it represents a non-volatile oxygenated heterocyclic species that may arise from synthetic side reactions, route-specific intermediate carryover, or oxidative transformation of the parent scaffold. Its polar functionality and limited chromophoric response typically require LC-MS/MS for trace-level measurement, with confirmatory LC-HRMS or NMR characterization where structural assignment is required. In impurity profiling, its presence is evaluated under process-related impurity control and, where applicable, aligned with ICH M7 principles for toxicological assessment.