115623-21-7Enalapril Diketopiperazine Acid

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Catalogue No.:	VL1360013
CAS No.:	115623-21-7
Mol. Formula:	C18H22N2O4
Mol. Weight:	330.38 g/mol

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Additional information on CAS 115623-21-7

Parent drug

Enalapril

IUPAC Name

(S)-2-((3S, 8aS)-3-methyl-1, 4-dioxohexahydropyrrolo[1, 2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid

Synonyms

(?S, 3S, 8aS)-Hexahydro-3-methyl-1, 4-dioxo-?-(2-phenylethyl)pyrrolo[1, 2-a]pyrazine-2(1H)-acetic Acid; [3S-[2(R*), 3?, 8a?]]-Hexahydro-3-methyl-1, 4-dioxo-?-(2-phenylethyl)pyrrolo[1, 2-a]pyrazine-2(1H)-acetic Acid;

Description

Enalapril Diketopiperazine Acid or (CAS No.115623-21-7) or (S)-2-((3S,8aS)-3-methyl-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid. Enalapril is a prodrug that is hydrolyzed after absorption to form the active angiotensin-converting enzyme Enalaprilat. It is administered orally. It decreases blood pressure by lowering peripheral resistance without increasing heart rate. It is well tolerated and safe. It is well tolerated and safe.

References

Davies, Richard O., et al. â€œEnalapril Worldwide Experience.â€ The American Journal of Medicine, vol. 77, no. 2, Aug. 1984, pp. 23â€“35, https://doi.org/10.1016/s0002-9343(84)80055-8. ?Todd, Peter A., and Karen L. Goa. â€œEnalapril.â€ Drugs, vol. 43, no. 3, Mar. 1992, pp. 346â€“81, https://doi.org/10.2165/00003495-199243030-00005.