Ibuprofen EP Impurity E, also known in pharmacopoeias as Ibuprofen Related Compund C, is a highly characterized reference material. It fully complies with stringent regulatory standards, including those set by USP, EMA, JP, and BP. This product is essential for use in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Ibuprofen. Moreover, it comes with a detailed Structure Elucidation Report (SER), ensuring its accuracy and reliability for a wide range of analytical applications. Also known as Ibuprofen Related Compound C, 4′-Isobutylacetophenone or p-Isobutylacetophenone is a harmful compound that can be formed photochemically from the anti-inflammatory drug ibuprofen. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that is extensively used as the active principle of many pharmaceutical products, including analgesics and antipyretics.
References
Ruggeri, Giulia, et al. “Photochemical Transformation of Ibuprofen into Harmful 4-Isobutylacetophenone: Pathways, Kinetics, and Significance for Surface Waters.” Water Research, vol. 47, no. 16, Oct. 2013, pp. 6109–21, https://doi.org/10.1016/j.watres.2013.07.031.
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