100% accuracy
of data
of data
24/7 scientific
support
support
0% tolerance in
quality of product
quality of product
Stock Locations
- New Jersey, USA
- Czech Republic, EU
- Mumbai, India
* Stock subject to availability.
65813-55-0Ibuprofen EP Impurity J
● In Stock
| Catalogue No.: | VL81003 |
|---|---|
| CAS No.: | 65813-55-0 |
| Mol. Formula: | C13H16O3 |
| Mol. Weight: | 220.26 g/mol |
Additional information on CAS 65813-55-0
Parent drug
IbuprofenIUPAC Name
(2RS)-2-[4-(2-Methylpropanoyl)phenyl]propanoic acidPharmacopeial Synonyms
Ibuprofen Related Compound J; Ibuprofen BP Impurity JSynonyms
Oxo Ibuprofen; 2-(4-Isobutyrylphenyl)propionic Acid; 1-Oxo Ibuprofen; 2-(4-Isobutyrylphenyl)propionic Acid; (+/-)-2-(4-(2-Methylpropanoyl)phenyl)propanoic acid; Benzeneacetic acid, alpha-methyl-4-(2-methyl-1-oxopropyl)-; alpha-Methyl-4-(2-methyl-1-oxopropyl)benzeneacetic AcidSmiles
CC(C1=CC=C(C(C(C)C)=O)C=C1)C(O)=OInChI
InChI=1S/C13H16O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9H,1-3H3,(H,15,16)Shipping Condition
Ambient TemperatureDescription
Ibuprofen EP Impurity J, also designated Ibuprofen Related Compound J and Ibuprofen BP Impurity J, corresponds to 1-Oxo Ibuprofen, a ketone oxidation product of the arylpropionic acid NSAID scaffold. CAS 65813-55-0 identifies the free acid form, with molecular formula C13H16O3 and molecular weight 220.26 g/mol. The impurity may arise through oxidative degradation or metabolic carbonyl formation at the side chain, rather than from a nitrosamine pathway. Structural assignment and low-level quantification generally require LC-MS/MS or high-resolution LC-MS, with confirmatory NMR and, where needed, GC-MS after derivatization. It is relevant to pharmacopeial impurity profiling and stability studies.References
YongFang Rao, Dan Xue, Huaimin Pan, Jiangtao Feng, Yingjie Li Container: Chemical Engineering Journal Year: 2016 Volume: 283 DOI: 10.1016/j.cej.2015.07.057 URL: https://www.sciencedirect.com/science/article/abs/pii/S1385894715010232Request a Quote
« * » indique les champs nécessaires
Other products related to Ibuprofen impurities
Impurity structure
Parent Drug Name
CAS No.
Name of Impurity
Catalog No.
