127780-16-9Pantoprazole EP Impurity A
● In Stock
| Catalogue No.: | VL125001 |
|---|---|
| CAS No.: | 127780-16-9 |
| Mol. Formula: | C16H15F2N3O5S |
| Mol. Weight: | 399.37 g/mol |
Order Online
Additional information on CAS 127780-16-9
Parent drug
PantoprazoleIUPAC Name
5-Difluoromethoxy-2-[[(3,4-dimethoxy)-2-pyridyl]methylsulfonyl]-1H-benzimidazolePharmacopeial Synonyms
Pantoprazole BP Impurity A; Pantoprazole Related Compound ASynonyms
Pantoprazole Sulfone; 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfonyl]-1H-benzimidazole; 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]; 1H-Benzimidazole, 6-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfonyl]Smiles
O=S(C1=NC2=CC(OC(F)F)=CC=C2N1)(CC3=NC=CC(OC)=C3OC)=OInChI
InChI=1S/C16H15F2N3O5S/c1-24-13-5-6-19-12(14(13)25-2)8-27(22,23)16-20-10-4-3-9(26-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)Shipping Condition
Ambient TemperatureDescription
Pantoprazole EP Impurity A, also designated Pantoprazole BP Impurity A, Pantoprazole Related Compound A, and Pantoprazole Sulfone, is the sulfoxide-oxidized degradation product of pantoprazole rather than a nitrosamine species. CAS 127780-16-9 identifies this benzimidazole sulfone impurity, molecular formula C16H15F2N3O5S, molecular weight 399.37 g/mol. Its formation is typically associated with oxidative stress during synthesis, storage, or exposure to peroxide-containing excipients. Because structurally related sulfone and sulfoxide species may co-elute, characterization commonly requires orthogonal LC-MS/MS, HPLC with diode-array detection, and, when necessary, high-resolution mass spectrometry for impurity profiling under pharmacopeial and ICH impurity control expectations.Request a Quote
« * » indique les champs nécessaires









