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2365312-75-8Azithromycin Impurity 3

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Catalogue No.:	VE0013055
CAS No.:	2365312-75-8
Mol. Formula:	C38H74N2O13
Mol. Weight:	767.01 g/mol

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Additional information on CAS 2365312-75-8

Parent drug

Azithromycin

IUPAC Name

(2R,3S,4S,5R,6R,8R)-5-(((2S,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-hydroxy-3-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2,4,6,8-tetramethyl-9-(methyl((2R,3R,4R,5R)-3,4,5-trihydroxy-4-methylheptan-2-yl)amino)nonanoic acid

Pharmacopoeial Synonyms

N/A

Other Synonyms

N/A

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

Description

Azithromycin Impurity 3, CAS 2365312-75-8, is a structurally related macrolide-related process or degradation impurity associated with azithromycin, the 15-membered azalide antibiotic. With molecular formula C38H74N2O13 and molecular weight 767.01 g/mol, it retains the characteristic desosamine and cladinose-derived polyoxygenated scaffold that can arise during synthetic transformation, epimerization, or hydrolytic alteration of the parent macrocycle. Its low-level presence may be monitored in stability and impurity profiling programs using orthogonal high-resolution LC-MS/MS, UHPLC with charged aerosol or evaporative light-scattering detection, and confirmatory LC-HRMS methods.