(2R)-2-[(4R)-2-Oxo-4-propylpyrrolidin-1-yl]butanamide, CAS 357337-00-9, is a chiral lactam-derived process impurity with molecular formula C11H20N2O2 and molecular weight 212.29 g/mol. The structure contains a substituted pyrrolidin-2-one linked to a butanamide fragment, consistent with formation during cyclization, alkylation, or incomplete resolution of related intermediates rather than oxidative degradation. Because of its stereochemical definition, enantiomeric purity may also be relevant in method development. Quantification generally relies on LC-MS/MS or high-resolution LC-MS, with orthogonal confirmation by NMR and, where needed, chiral LC to assess isomeric impurities under ICH M7-aligned impurity control expectations.
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