4-Propylpyrrolidin-2-one
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

89895-19-24-Propylpyrrolidin-2-one

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Catalogue No.:VE0010191
CAS No.:89895-19-2
Mol. Formula:C7H13NO
Mol. Weight:127.18 g/mol

Additional information on CAS 89895-19-2

Parent drug

Brivaracetam

IUPAC Name

4-Propylpyrrolidin-2-one

Synonyms

N/A

Description

It is one of impurity present in Brivaracetam, Brivaracetam is a racetam derivative of levetiracetam, Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam, and SV2A is act on epileptogenesis through modulation of synaptic GABA release, by that brivaracetam exerts its anti-epileptogenic effects through its binding to SV2A. Brivaracetam is also known to inhibit Na+ channels which may also contribute to its anti-epileptogenic action, which is used in the treatment of partial-onset seizures.

References

Feyissa, A. M. (2019). Brivaracetam in the treatment of epilepsy: a review of clinical trial data. Neuropsychiatric Disease and Treatment, Volume 15, 2587–2600. https://doi.org/10.2147/ndt.s143548

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