7458-08-4: Clomipramine EP Impurity E Nitroso Impurity

Also known as N-Nitrosoiminodibenzyl, it is an impurity present in Clomipramine. Clomipramine is a dibenzazepine derivative tricyclic antidepressant, that works exclusively by inhibiting the reuptake of the neurotransmitters norepinephrine and serotonin by nerve cells. It is thought that changes occur in receptor sensitivity in the cerebral cortex and hippocampus. The hippocampus is part of the limbic system a part of the brain involved in emotions. which is an effective analgesic for different types of pain, especially neuropathic or neuralgic pain.

Additional information

Catalogue No.

VE009769

CAS No.

7458-08-4

Molecular Formula

C14H12N2O

Molecular Weight

224.26 g/mol

IUPAC Name

10, 11-Dihydro-5-nitroso-5H-dibenz[b, f]azepine

Synonyms

N-Nitrosoiminodibenzyl

Status

In-stock

References

Wilson, M., & Tripp, J. (2022, May 10). Clomipramine. Retrieved November 1, 2022, from Nih.gov website: https://www.ncbi.nlm.nih.gov/books/NBK541006/