83482-58-0: 27-demethoxyrapamycin

It is one of impurity present in Rapamycin. which is a macrocyclic lactone antibiotic produced by the bacteria Streptomyces hygroscopicus, Its mechanism of action is the inhibition of the mammalian target of rapamycin, which is a threonine-specific protein kinase that regulates cell growth. which is used to regulate longevity and maintain normal glucose homeostasis. Targeting mTOR received more attention especially in cancer as mTOR signaling pathways are constitutively activated in many types of human cancer. Is an antifungal agent with potent anticandida activity also it is a potent antitumor and immunosuppressive activity.

Additional information on CAS 83482-58-0

Catalogue No.

VE009051

CAS No.

83482-58-0

Molecular Formula

C50H77NO12

Molecular Weight

884.2 g/mol

Parent drug

Rapamycin

IUPAC Name

27-demethoxyrapamycin

Synonyms

N/A

References

Ehninger, D., Neff, F., & Xie, K. (2014). Longevity, aging and rapamycin. Cellular and Molecular Life Sciences, 71(22), 4325–4346. https://doi.org/10.1007/s00018-014-1677-1

Status

In-stock

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83482-58-0: 27-demethoxyrapamycin

83482-58-0: 27-demethoxyrapamycin
Catalogue No.

VE009051

CAS No.

83482-58-0

Molecular Formula

C50H77NO12

Molecular Weight

884.2 g/mol

Parent drug

Rapamycin

IUPAC Name

27-demethoxyrapamycin

Synonyms

N/A

References

Ehninger, D., Neff, F., & Xie, K. (2014). Longevity, aging and rapamycin. Cellular and Molecular Life Sciences, 71(22), 4325–4346. https://doi.org/10.1007/s00018-014-1677-1

Status

In-stock

ListName

27-demethoxyrapamycin

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