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1231930-82-7Abemaciclib Mesylate
● Under Development
| Catalogue No.: | VL4990001 |
|---|---|
| CAS No.: | 1231930-82-7 |
| Mol. Formula: | C₂₈H₃₆F₂N₈O₃S |
| Mol. Weight: | 602.7 g/mol |
Additional information on CAS 1231930-82-7
Parent drug
AbemaciclibIUPAC Name
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine MethanesulfonatePharmacopoeial Synonyms
N/AOther Synonyms
Abemaciclib Methanesulfonate; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate; 2-Pyrimidinamine, N-(5-((4-ethyl-1-piperazinyl)methyl)-2-pyridinyl)-5-fluoro-4-(4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl)-, methanesulfonate (1:1); N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;methanesulfonic acid; Methanesulfonic acid–N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amine (1/1)Description
Abemaciclib Mesylate (CAS No: 1231930-82-7) belonging to the class of Aminopyridines is an inhibitor of cyclin-dependent kinases 4 and 6 that is used in the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.References
Kim, Esther S. “Abemaciclib: First Global Approval.” Drugs, vol. 77, no. 18, Nov. 2017, pp. 2063–70, https://doi.org/10.1007/s40265-017-0840-z.Request a Quote
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Impurity structure
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