50725-24-1: Amikacin EP Impurity A

Status: Under Development

It is an impurity detected in Amikacin that is a semisynthetic analog of kanamycin, which is utilized in the treatment against gram-negative bacteria including gentamicin- and tobramycin-resistant strains.

Additional information on CAS 50725-24-1

Catalogue No. VL6230001
CAS No. 50725-24-1
Molecular Formula C22H43N5O13
Molecular Weight 585.60 g/mol
Parent drug Amikacin
IUPAC Name 4-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-6-O-(6-amino-6-deoxy-α-D-glucopyranosyl)-1-N-[(2S)-4-amino-2-hydroxybutanoyl]-2-deoxy-L-streptamine
Synonyms N/A
References Ristuccia AM, Cunha BA. An overview of amikacin. Therapeutic Drug Monitoring. 1985 ;7(1):12-25. DOI: 10.1097/00007691-198503000-00003. PMID: 3887667.http://europepmc.org/article/med/3887667 Wang, Jian, et al. “Separation and Characterization of Unknown Impurities in Amikacin Sulfate by HPLC–MS N.” ResearchGate, Springer Nature, 30 Aug. 2015, http://www.researchgate.net/publication/277921697_Separation_and_Characterization_of_Unknown_Impurities_in_Amikacin_Sulfate_by_HPLC-MS_n. Accessed 27 Oct. 2023.
Status Under Development

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