Amlodipine Impurity 20
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

70677-78-0Amlodipine Impurity 20

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Catalogue No.:VL19018
CAS No.:70677-78-0
Mol. Formula:C17H19NO4
Mol. Weight:301.34 g/mol

Additional information on CAS 70677-78-0

Parent drug

Amlodipine

IUPAC Name

dimethyl 2, 6-dimethyl-4-phenyl-1, 4-dihydropyridine-3, 5-dicarboxylate

Smiles

CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2)C(=O)OC

Synonyms

N/A

Description

Amlodipine Impurity 20(CAS No: 70677-78-0) or dimethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate is impurity amlodipine which is the 3rd generation of dihydropyridine.it acts as an inhibition of calcium influx into vascular smooth muscle cells and myocardial cells it is highly used to reduce blood pressure.

References

Chan, Xin Hui S., et al. The Cardiovascular Effects of Amodiaquine and Structurally Related Antimalarials: An Individual Patient Data Meta-Analysis.” PLoS Medicine, vol. 18, no. 9, Sept. 2021, p. e1003766, https://doi.org/10.1371/journal.pmed.1003766.

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