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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

Budesonide Oxoacetic Acid

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Catalogue No.:	VE007474
CAS No.:	N/A
Mol. Formula:	C25H32O7
Mol. Weight:	444.52 g/mol

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Additional information on Budesonide Oxoacetic Acid

Parent drug

Budesonide

IUPAC Name

2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-6a,8a-dimethyl-4-oxo-10-propyl-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2′,1′:4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoacetic acid

Synonyms

Budesonide Related Compound 5

Description

Budesonide Oxoacetic Acid, also designated Budesonide Related Compound 5, is an oxidative degradant of the corticosteroid budesonide arising from side-chain oxidation to a ketocarboxylic acid motif. This impurity is not a nitrosamine or mutagenic alkylating species, yet its presence is relevant for impurity profiling and stability assessment under pharmaceutical regulatory expectations. The compound has formula C25H32O7 and molecular weight 444.52 g/mol. Owing to closely related steroidal polarity and limited UV selectivity, determination commonly requires LC-MS/MS with confirmatory high-resolution mass spectrometry, complemented by chromatographic resolution on reversed-phase systems and, where necessary, NMR characterization of the oxoacetic functionality.