773-76-2: Clioquinol EP Impurity B

Clioquinol EP Impurity B (CAS No: 773-76-2) or Chloroxine mutates and depresses DNA damage tolerance to reinstate platinum sensitivity in high-grade serous ovarian cancer. Chloroxine conjugates silver nanoflowers that show assuring antimicrobial activity and in vivo cutaneous wound healing effects.

Additional information

Catalogue No.

VE006809

CAS No.

773-76-2

Molecular Formula

C9H5Cl2NO

Molecular Weight

214.05

IUPAC Name

5, 7-Dichloroquinolin-8-ol

Synonyms

Chloroxine

References

Silva, Vera L., et al. “Chloroxine Overrides DNA Damage Tolerance to Restore Platinum Sensitivity in High-Grade Serous Ovarian Cancer.” Cell Death & Disease, vol. 12, no. 4, Apr. 2021, https://doi.org/10.1038/s41419-021-03665-0. ‌Shahabadi, Nahid, et al. “Green Synthesis of Chloroxine-Conjugated Silver Nanoflowers: Promising Antimicrobial Activity and in Vivo Cutaneous Wound Healing Effects.” Journal of Environmental Chemical Engineering, vol. 9, no. 3, June 2021, p. 105215, https://doi.org/10.1016/j.jece.2021.105215. ‌

Status

In-stock